Mice in modern medicine

Experts said that mice are not specific to the key purpose for research and treatment and medicines manufactured, not through them to solveanswer all the difficult problems of modern medicine. Mice to 10 thousand dollars worth Because the gene structure and chassis system structure of the mouse gene similar to human genes, the mice became "the pillar between the lines for scientists to explore research and disease detection and treatment for the new medicine. Mouse cancer, mouse diabetes, heart ... rats, known as the kind of "special mouse" has been "manufactured" for scientific research. There are special mice to 10 thousand dollars worth. "Factory" producing special mouse Limited by many scientists and pathological study of experimental medicine in the world is not self-breeding rodent request that they be ordered. America is one of the few national pioneers in manufacturing research to create mice carrying the disease like a disease to be studied for drug treatment and testing. They call research facilities produce this special type of mouse as "Mouse Factory". For years, experts working in the "factory rats" have used modern biotechnology to produce a large assortment of "special mice" - mice infected with all manner of diseases. The scientists of the "factory rats" that use artificial methods or natural conduct appropriate and reasonable control for a gene or a group of mice, can result, creating breeding mice that carry any disease like a disease. It is known that at present each year in scientific research have used up to 25 million rats in particular. Jackson Laboratory Maine, USA is a reputable establishments providing mouse for scientific research, over 2 million per year of the mouse. Charike laboratory in Winminton, Massachusetts specializes in providing millions of animals in particular, which are mainly rats for scientific research institutions and drug companies processed each year earnings due to the dynamic consumption this material to nearly $ 1 billion. Breeding "special mouse" based on the key technical achievements The bill "Biomedical America" provisions for scientific research using mice and rats bred especially challenging, so the experimental mice with individual institutions, will be granted quotas of foreign currency shortages. The first half of the twentieth century, experimental mouse reproduction is very simple, just be careful nurturing. But the scientific research currently use the mouse to play the "special role" more and more, the mice are reared in line with requirements of the different labs is not easy. Requires the involvement of key techniques of modern biology, and also requires thorough knowledge of techniques for mass logistics nurture high-tech. In 2001, after scientists completed universal human gene map, then immediately after, in 2002 was quickly complete spectrum of mouse DNA map, has brought new significance for scientific research using mice Mouse breeding and special techniques. In the first half of the twentieth century, when scientists used mice as experimental reproductive studies, they basically do not know what DNA is, the gene concept is very vague. This popular charts with the achievements of DNA, when compared correlation sequence human and mouse genes, they found problems that had previously always been clear question: in fact the human and mouse genes is the same, where the difference is not in the genes themselves but in time, place and way in which genes are activated. Wocheke Ricke, Director Jackson Laboratory, the U.S. said: "One of the universal meaning of human and mouse DNA map is to bring awareness to anatomy and physiology of mice and humans are very similar" . Feeding mice with genetic characteristics of very expensive Nixion, genetic researchers said recent decades, research in breeding mice, each mouse can be allowed to create a certain outstanding features, which can be used to provide specialized testing Specific. Once it detects any unusual mouse, it is a new varieties and will be able to produce a new direction to study genetic characteristics. To study a new generation of mice, scientists depending on the requirements that can add or eliminate one or several genes of mice. As revealed, along with the creation of mice with specific genes, gene Delta Company, California also breeding mice Specific genetic defects, drug companies producing Colorternis also studied mice that were transplanted genes of ... With technology and genetic engineering controls, to nurture a particular gene to mice often very expensive, sometimes up to tens of thousands of dollars. But once "production line" is mouse specific comments and complete set can produce large profits also increased significantly. Austin, director of GM Research Center under the Department of Health Research, said the United States: in 2006, two biotechnology companies in this office has spent $ 10 million to buy 250 types of mice with the genetic characteristics related to Their physiological parameters, it is more just the initial expenditure of research items. Mice carrying the genetic characteristics help research diseases and produce medicines Some researchers suggest that the use of specific mouse genes, can not a few studies that new medicine. To explore new medicine, first determine the "target", according to biologists, it is a target biomolecule, it plays an important role in the pathogenic process, but at the same time it can be inhibited or affected by chemical compounds that are relatively harmless. Mice carrying the genetic characteristics are considered "factory target"; it that a genetic defect, is a specialty of molecular biology. For example, researchers discovered a mouse that despite how much food is "skinny"; through analysis of mouse genes will be able to find fat gene correlation, based on the gene "targets "to research and manufacture drugs to reduce fat, this is a major breakthrough in computer science research. Experts said that from 5000 genes in the mouse features detected only a few dozen "target," well, can also ripped open a revolution in manufacturing medicines. Deputy Director of Lekexon genes, U.S. says, easy to consume 100 drugs on the market today is the result of the studies identified a few dozen "targets" on the mouse, it said on the importance breeding mice for research on how specific. The experts also said that special mouse is not the key to universal treatment for research and manufacture pharmaceuticals, not through them to solve all the problems of modern medicine. But in this process, the mouse features have played an important role and need time for testing. TL (The Science)

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